Starving Cancer with a Low Methionine Diet - Greger
Forty years ago, a landmark paper was published showing for the first time that many human cancers have what’s called “absolute methionine dependency,” meaning that if we try to grow cells in a Petri dish without giving them the amino acid methionine, normal cells thrive, but without methionine, cancer cells die. Normal breast cells grow no matter what, with or without methionine, but cancer cells need that added methionine to grow.
Fresh tumors taken from patients show that many cancers appear to have a biochemical defect that makes them dependent on methionine, including some tumors of the colon, breast, ovary, prostate, and skin. Pharmaceutical companies are fighting to be the first to come out with a drug that decreases methionine levels. But since methionine is sourced mainly from food, a better strategy may be to lower methionine levels by lowering methionine intake, eliminating high methionine foods to control cancer growth as well as improve our lifespan (see Methionine Restriction as a Life-Extension Strategy).
So, where is methionine found? In my video, Starving Cancer with Methionine Restriction, you can see a graph of foods with their respective methionine levels. Chicken and fish have the highest levels. Milk, red meat, and eggs have less, but if we really want to stick with lower methionine foods, fruits, nuts, veggies, grains, and beans are the best. In other words, “In humans, methionine restriction may be achieved using a predominately vegan diet.”